Repeated DNA Sequences

来源:互联网 发布:淘宝卖家怎么联系快递 编辑:程序博客网 时间:2024/05/21 09:34

All DNA is composed of a series of nucleotides abbreviated as A, C, G, and T, for example: "ACGAATTCCG". When studying DNA, it is sometimes useful to identify repeated sequences within the DNA.

Write a function to find all the 10-letter-long sequences (substrings) that occur more than once in a DNA molecule.

For example,

Given s = "AAAAACCCCCAAAAACCCCCCAAAAAGGGTTT",Return:["AAAAACCCCC", "CCCCCAAAAA"].

Subscribe to see which companies asked this question.

解题技巧:

       该题主要采用了两种技巧:位运算、hash。

       考虑将ACGT进行二进制编码,即:A -> 00, C -> 01, G -> 10, T -> 11;在编码的情况下,每10位字符串的组合即为一个数字,且10位的字符串有20位,一般来说int有4个字节,32位,即可以用于对应一个10位的字符串。例如:ACGTACGTAC -> 00011011000110110001

       20位的二进制数,至多有2^20种组合,因此hash table的大小为2^20,即1024 * 1024,将hash table设计为bool hashTable[1024 * 1024];

       在处理字符串时,每次向右移动1位字符,相当于字符串对应的int值左移2位,再将其最低2位置为新的字符的编码值,最后将高2位置0;得到当前的子字符串对应的值val后,判断该值是否出现过,如果未出现,则将hasTable[val]设置为true,否则,将当前的子字符串存入到set容器中

代码:

#include <iostream>#include <string>#include <vector>#include <set>#include <mem.h>#include <map>using namespace std;vector<string> findRepeatedDnaSequences(string s){    vector<string> res;    if(s.length() < 10) return res;    map<char,int> mp;    mp['A'] = 0;    mp['C'] = 1;    mp['G'] = 2;    mp['T'] = 3;    bool exist[1024*1024];    memset(exist, false, sizeof(exist));    int val = 0;    for(int i = 0; i < 10; i ++)    {        val <<= 2;        val |= mp[s[i]];    }    exist[val] = true;    set<string> tmp;    for(int i = 10; i < s.length(); i ++)    {        val <<= 2;        val |= mp[s[i]];        val &= ~(0x300000);        if(exist[val]) tmp.insert(s.substr(i-9,10));        else exist[val] = true;    }    set<string>::iterator it = tmp.begin();    while(it != tmp.end())    {        res.push_back(*it);        it++;    }    return res;}int main(){    vector<string> res;    string s;    cin >> s;    res = findRepeatedDnaSequences(s);    for(int i = 0; i < res.size(); i ++)    {        cout<<res[i]<<' ';    }}


原创粉丝点击